|
KMID : 0644120180310010043
|
|
Journal of Oriental Gynecology
2018 Volume.31 No. 1 p.43 ~ p.56
|
|
|
Screening Herbal Decoction of the Vascular Relaxation in Korean Medicine
|
|
Kim Hye-Yoom
Seo Chang-Seob
Shin Hyeun-Kyoo
Hong Mi-Hyeon
Yoon Jung-Joo
Ahn You-Mee
Eun So-Young
Lee Yun-Jung
Lee Ho-Sub
Kang Dae-Gill
|
|
|
Abstract
|
|
|
Objectives: This study was designed to investigate the basis for developing the herbal decoction that may help promote healthy blood vessels in accordance with the basic principles of Korean medicinal materials.
Methods: In this study, we investigated the vascular relaxation effects of fifty herbal decoctions on vascular response in isolated thoracic aorta of phenylephrine-preconracted rats.
Results: The results of identify the vascular relaxation effect of fifty herbal decoctions provided by Korea Institute of Korean Medicine, twenty-one herbal decoctions showed vascular relaxation effects. Among them, four herbal decoctions, Mahwang-tang (麻黃湯), Samchulgeonbi-tang (參朮健脾湯), Cheonwangbosim-dan (天王補心丹), and Socheonglyong-tang (小靑龍湯), with showed significantly concentration- dependent vasodilation was examined. Vascular relaxation level are 84.02±4.70, 79.39±13.99, 51.26±12.56, and 54.73±15.88%, respectively (P<0.05, 0.01, and 0.001).
Conclusions: Thus these results provide a basic data for the treatment of the impairment of vascular function and blood pressure in traditional Oriental medicine.
|
|
|
KEYWORD
|
|
|
Herbal Decoction, Vascular Relaxation, Vasodilation, Blood Vessel, Thoracic Aorta
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|
|